EXPERIMENTAL CONGENITAL TOXOPLASMOSIS
نویسندگان
چکیده
منابع مشابه
Experimental Congenital Toxoplasmosis
Pregnant mice infected with Toxoplasma by the vaginal route have been found to transmit toxoplasmosis to the placentas and fetuses in utero. The microorganism entered the blood stream of the mother from primary foci of infection in the vaginal wall and produced disseminated lesions in the labyrinth of the allantoic placenta at the same time as other peripheral maternal tissues were involved. Pl...
متن کاملCongenital toxoplasmosis.
Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...
متن کاملCongenital toxoplasmosis.
The history of toxoplasmosis began in 1923 with the F first published description of a human case, a congenitally infected baby. Toxoplasma gondii had been recognised 15 years earlier, but it was not until 1%96 that the life cycle of this protozoan parasite was understood, with the discovery that the definitive host : was any member of the cat family (fig 1).' 2 _ Despite extensive clinical and...
متن کامل[Congenital toxoplasmosis].
Since congenital toxoplasmosis was first recognized as a human infection 18 years ago, it has been found in many parts of the world, and, following the first report by Jacoby and Sagorin in 1948, over 50 cases have been recorded in the British literature. Only four of the reports from this country concern the findings in fatal cases (Cathie and Dudgeon, 1949; Valentine, 1952; Valentine, Lane, B...
متن کاملExperimental congenital toxoplasmosis in Wistar and Holtzman rats.
Congenital toxoplasmosis was evaluated in Wistar and Holtzman rats using two strains of Toxoplasma gondii isolated in Brazil. Pregnant rats were inoculated by subcutaneous or intraperitoneal routes with 10(6) or 8 x 10(6) tachyzoites of N strain (virulent for mice) and by subcutaneous or oral routes with 10(2) or 1.2 x 10(3) cysts of P strain (avirulent for mice). The tissues of rat pups born f...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1950
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.92.5.393